# Boltz

First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed. Boltz is free, with no paid plan attached, at github.com.

## Facts

- **Pricing tier:** Free
- **Works on:** Self-hosted, CLI
- **Works in browser:** No

## Capabilities

- First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed
- Boltz-2 adds binding-affinity prediction, not just structure
- Hostable free via community web apps (e.g. Tamarind Bio) or run locally

## FAQ

### What is Boltz?

Boltz is listed under Science & Research AI, in the Research & Learning category on Flocci AI Tools. First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed. It is free, with no paid plan attached, and it lives at github.com.

### Is Boltz free?

Boltz is listed as fully free — there is no paid tier attached to it in the catalog. That makes it one of the 396 entries on Flocci AI Tools with no upgrade path built in.

### Can I use Boltz in a browser, or is there an app?

Boltz needs to be installed or self-hosted — it doesn't run in a browser tab. It is available on self-hosting and the command line.

### What can Boltz do?

Boltz does 3 things the catalog singles out: First fully open-source model to approach alphafold3-level structure prediction, mit-licensed; boltz-2 adds binding-affinity prediction, not just structure; hostable free via community web apps (e.g. tamarind bio) or run locally.

### What is the best free alternative to Boltz?

AlphaFold Server is the closest free alternative: it sits in the same Science & Research AI sub-category and is free. Biomni, AI Scientist-v2 and Evo 2 also start free. The full list is on the alternatives page.

## Related

- [Boltz alternatives](https://aitools.flocci.in/alternatives/boltz)
- [Science & Research AI](https://aitools.flocci.in/category/research-learning/science-research-ai)
- [Best free AI tools for science and research](https://aitools.flocci.in/best/best-science-research-ai)
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Source: Flocci AI Tools — https://aitools.flocci.in/tool/boltz

Facts last verified: October 2026