Agno vs DSPy

Agno is free, with no paid plan attached. DSPy is free, with no paid plan attached. Both are listed under Agent Frameworks (Developers), so this is a like-for-like comparison. Neither is ranked above the other — Flocci carries no sponsored placement.

Agno vs DSPy — straight answers

Agno vs DSPy: what is the difference?

Agno is free, with no paid plan attached and is listed for open-source (Apache-2.0) Python framework, 41.7k GitHub stars. DSPy is free, with no paid plan attached and is listed for open-source (MIT) framework from Stanford NLP, 37k+ GitHub stars. Both sit in Agent Frameworks (Developers).

Is Agno or DSPy cheaper to start with?

Neither — Agno and DSPy are both free, so the choice comes down to capability rather than cost. Both entries list what they uniquely do above.

Which should I choose, Agno or DSPy?

Choose Agno if you need open-source (Apache-2.0) Python framework, 41.7k GitHub stars; choose DSPy if you need open-source (MIT) framework from Stanford NLP, 37k+ GitHub stars. Flocci AI Tools does not rank one above the other — it shows both feature sets side by side and lets the requirement decide.

Agno compared with DSPy: pricing tier, category, listed capabilities and links.
 AgnoDSPy
Pricing tierFreeFree
Free to startYesYes
CategoryAI Agents & AutomationAI Agents & Automation
TypeAgent Frameworks (Developers)Agent Frameworks (Developers)
Listed capabilities
  • Open-source (Apache-2.0) Python framework, 41.7k GitHub stars
  • AgentOS: FastAPI-based production runtime for deploying agents
  • Control-plane UI for monitoring live agent systems across clouds
  • Open-source (MIT) framework from Stanford NLP, 37k+ GitHub stars
  • Compiles/optimizes prompts automatically against metrics instead of manual prompt tuning
  • Production use at Databricks, Shopify, Dropbox, AWS; Shopify reports ~550x cost reduction
Tagsagno agent framework, phidata successor, agent runtime, open source agents, agentos, python agentsdspy stanford, prompt optimization framework, program not prompt, open source llm framework, structured signatures, python
Websiteagno.comdspy.ai
Full pageAgno details →DSPy details →
AlternativesAgno alternatives →DSPy alternatives →

AWS Strands Agents

Agent Frameworks (Developers)
free
  • Open-source (6,800+ stars) Python and TypeScript SDK from AWS
  • Steering handlers/hooks that catch agent mistakes before execution
  • Native Bedrock and AWS AgentCore integration, plus any-LLM support

Google Agent Development Kit (ADK)

Agent Frameworks (Developers)
free
  • Open-source Python/Java framework from Google for building multi-agent systems
  • Native integration with Vertex AI Agent Engine and Gemini models
  • Model-agnostic — works with non-Google LLMs via LiteLLM

LangGraph

Agent Frameworks (Developers)
free
  • Build stateful, multi-agent apps as graphs
  • Human-in-the-loop and durable execution
  • Works with any LLM
  • Open-source with a hosted platform

Mastra

Agent Frameworks (Developers)
free
  • Open-source TypeScript framework (Apache 2.0) for agents, workflows and RAG
  • Drops directly into existing React/Next.js apps or runs standalone
  • Built-in workflow engine with suspend/resume and human-in-the-loop steps

Microsoft AutoGen

Agent Frameworks (Developers)
free
  • Multi-agent conversation framework
  • Event-driven, async agent design
  • Studio UI for prototyping
  • Fully open-source

OpenAI Agents SDK

Agent Frameworks (Developers)
free
  • Lightweight agent orchestration from OpenAI
  • Agent handoffs, guardrails and tracing
  • Tool and function calling built in
  • Open-source, pay only for model usage