Science & Research AIfreemium

Chai-1 (Chai Discovery)

Chai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model

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What Chai-1 (Chai Discovery) does

  • Chai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model
  • Chai-2 (paid, enterprise) generates de novo antibodies directly from target epitopes, used by Lilly, Novartis, Pfizer

Chai-1 (Chai Discovery) — straight answers

What is Chai-1 (Chai Discovery)?

Chai-1 (Chai Discovery) is listed under Science & Research AI, in the Research & Learning category on Flocci AI Tools. Chai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model. It is freemium — a usable free tier with paid plans above it, and it lives at chaidiscovery.com.

Is Chai-1 (Chai Discovery) free?

Chai-1 (Chai Discovery) is freemium: there is a free tier you can work in and paid plans above it. It is one of 426 freemium tools in the catalog, all labelled the same way so you are never surprised by a paywall.

Can I use Chai-1 (Chai Discovery) in a browser, or is there an app?

Chai-1 (Chai Discovery) works in a normal browser tab with no install. It is available on the web and self-hosting.

What can Chai-1 (Chai Discovery) do?

Chai-1 (Chai Discovery) does two things the catalog singles out: Chai-1 is free, apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model; chai-2 (paid, enterprise) generates de novo antibodies directly from target epitopes, used by lilly, novartis, pfizer.

What is the best free alternative to Chai-1 (Chai Discovery)?

AlphaFold Server is the closest free alternative: it sits in the same Science & Research AI sub-category and is free. Biomni, AI Scientist-v2 and Boltz also start free. The full list is on the alternatives page.

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Chai-1 (Chai Discovery) alternatives

Compare all alternatives →

AlphaFold Server

Science & Research AI
free
  • Free browser-based access to AlphaFold 3-class structure prediction for non-commercial research
  • Predicts structure/interactions of proteins, DNA, RNA, ligands in one model
  • Backed by the AlphaFold Protein Structure Database of 200M+ predicted structures
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Boltz

Science & Research AI
free
  • First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed
  • Boltz-2 adds binding-affinity prediction, not just structure
  • Hostable free via community web apps (e.g. Tamarind Bio) or run locally
Visit
  • Autonomous AI agent that runs literature review + data analysis cycles, condensing ~6 months of research into a day per vendor
  • Publicly available via web interface and API, not an internal-only research demo
  • Kosmos itself requires a paid subscription; the free plan covers only standard agents.
Visit

Biomni

Science & Research AI
freeNew
  • General-purpose biomedical agent combining LLM planning with code execution
  • Integrates 150+ bioinformatics tools and 59 databases
  • Web interface so biologists can use it without coding
  • Open-source from Stanford SNAP lab
Visit

Evo 2

Science & Research AI
freeNew
  • DNA language model at single-nucleotide resolution with 1M base-pair context
  • Variant effect prediction, sequence completion and genome design
  • Free hosted 40B access via NVIDIA build.nvidia.com
  • Apache 2.0 code, weights and training data open; published in Nature
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AI Scientist-v2

Science & Research AI
freeNew
  • Agentic tree search proposes ideas, runs experiments and writes papers
  • No human-authored templates needed
  • Open code from Sakana AI
  • Requires disclosure of AI use in resulting papers
Visit

Head-to-head comparisons

Chai-1 (Chai Discovery) vs AlphaFold ServerChai-1 (Chai Discovery) vs BoltzChai-1 (Chai Discovery) vs Kosmos (Edison Scientific / FutureHouse)Chai-1 (Chai Discovery) vs BiomniChai-1 (Chai Discovery) vs Evo 2Chai-1 (Chai Discovery) vs AI Scientist-v2