Research & Learning (6)

6 free AI tools for science and research and 1 more — pricing tier and real capabilities on every entry. No ads, no sponsored placement.

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AlphaFold Server

Science & Research AI
free
  • Free browser-based access to AlphaFold 3-class structure prediction for non-commercial research
  • Predicts structure/interactions of proteins, DNA, RNA, ligands in one model
  • Backed by the AlphaFold Protein Structure Database of 200M+ predicted structures
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Boltz

Science & Research AI
free
  • First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed
  • Boltz-2 adds binding-affinity prediction, not just structure
  • Hostable free via community web apps (e.g. Tamarind Bio) or run locally
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Chai-1 (Chai Discovery)

Science & Research AI
freemium
  • Chai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model
  • Chai-2 (paid, enterprise) generates de novo antibodies directly from target epitopes, used by Lilly, Novartis, Pfizer
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Biomni

Science & Research AI
freeNew
  • General-purpose biomedical agent combining LLM planning with code execution
  • Integrates 150+ bioinformatics tools and 59 databases
  • Web interface so biologists can use it without coding
  • Open-source from Stanford SNAP lab
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Evo 2

Science & Research AI
freeNew
  • DNA language model at single-nucleotide resolution with 1M base-pair context
  • Variant effect prediction, sequence completion and genome design
  • Free hosted 40B access via NVIDIA build.nvidia.com
  • Apache 2.0 code, weights and training data open; published in Nature
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AI Scientist-v2

Science & Research AI
freeNew
  • Agentic tree search proposes ideas, runs experiments and writes papers
  • No human-authored templates needed
  • Open code from Sakana AI
  • Requires disclosure of AI use in resulting papers
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Science & Research AI — straight answers

What are the best free AI tools for science and research?

Flocci AI Tools lists 7 AI tools for science and research, ordered free tiers first: AlphaFold Server, Biomni, AI Scientist-v2, Boltz and Evo 2. 6 of the 7 are free or have a free tier. Every entry states what it uniquely does, not a score.

Are there completely free AI tools for science and research?

Yes — 5 of these are marked fully free with no paid plan attached: AlphaFold Server, Biomni, AI Scientist-v2, Boltz and Evo 2. The rest are freemium, trial or paid, and each row states which.

What should I look for in AI tools for science and research?

Start with what you need to do: predict structures and reason over experimental data. Then check the pricing tier, because "free" here means no paid plan at all while "freemium" means a free tier under paid plans. Every tool on this page lists both.

See the full list →

Head-to-head comparisons

AlphaFold Server vs BiomniAI Scientist-v2 vs AlphaFold ServerAlphaFold Server vs BoltzAlphaFold Server vs Evo 2AlphaFold Server vs Chai-1 (Chai Discovery)AI Scientist-v2 vs BiomniBiomni vs BoltzBiomni vs Evo 2

Free alternatives

AlphaFold Server alternativesBoltz alternativesChai-1 (Chai Discovery) alternativesBiomni alternativesEvo 2 alternativesAI Scientist-v2 alternatives

Looking for a ranked shortlist instead? See the best free AI tools for science and research.