The best free AI tools for science and research (7)

Every option in the catalog for when you need to predict structures and reason over experimental data — 7 AI tools for science and research, 6 of them free or freemium, with the pricing tier printed on every row.

7tools listed
6free or freemium
5with no paid plan at all
1sub-categories covered

Best Free AI tools for science and research — straight answers

What are the best free AI tools for science and research?

Flocci AI Tools lists 7 of them, ordered free tiers first: AlphaFold Server, Biomni, AI Scientist-v2, Boltz and Evo 2. 6 of the 7 are free or have a free tier. Each entry states what it uniquely does rather than a score.

Which of these are completely free?

5 on this page are marked fully free with no paid plan at all: AlphaFold Server, Biomni, AI Scientist-v2, Boltz and Evo 2. The remaining 2 are freemium, trial or paid, and each is labelled with its exact tier so nothing surprises you at sign-up.

How is this list ordered?

Free tools first, then freemium, then trial, then paid, and alphabetically inside each tier. Nobody pays to appear higher: Flocci AI Tools carries no ads, no sponsored slots and no paid listings, so the order reflects price and nothing else.

Best Free AI tools for science and research — quick picks

Which AI tools for science and research work in a browser with no install?

AlphaFold Server, Biomni and Chai-1 (Chai Discovery) all work in a browser tab with no install needed — just open the site and go. 3 of the 6 free AI tools for science and research listed here are browser-based.

Which AI tools for science and research can you self-host or run offline?

AI Scientist-v2, Boltz and Evo 2 can be self-hosted or run locally without a browser — useful for privacy, air-gapped networks, or avoiding API rate limits. 3 of the 6 free AI tools for science and research here run offline.

All 7 tools, free tiers first

Browse Science & Research AI →
Best Free AI tools for science and research: pricing tier, category and the capability each tool is listed for.
ToolPricingTypeListed for
AlphaFold ServerFreeScience & Research AIFree browser-based access to AlphaFold 3-class structure prediction for non-commercial research
BiomniFreeScience & Research AIGeneral-purpose biomedical agent combining LLM planning with code execution
AI Scientist-v2FreeScience & Research AIAgentic tree search proposes ideas, runs experiments and writes papers
BoltzFreeScience & Research AIFirst fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed
Evo 2FreeScience & Research AIDNA language model at single-nucleotide resolution with 1M base-pair context
Chai-1 (Chai Discovery)FreemiumScience & Research AIChai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model
Kosmos (Edison Scientific / FutureHouse)Science & Research AIAutonomous AI agent that runs literature review + data analysis cycles, condensing ~6 months of research into a day per vendor

AlphaFold Server

Science & Research AI
free
  • Free browser-based access to AlphaFold 3-class structure prediction for non-commercial research
  • Predicts structure/interactions of proteins, DNA, RNA, ligands in one model
  • Backed by the AlphaFold Protein Structure Database of 200M+ predicted structures

Biomni

Science & Research AI
freeNew
  • General-purpose biomedical agent combining LLM planning with code execution
  • Integrates 150+ bioinformatics tools and 59 databases
  • Web interface so biologists can use it without coding
  • Open-source from Stanford SNAP lab

AI Scientist-v2

Science & Research AI
freeNew
  • Agentic tree search proposes ideas, runs experiments and writes papers
  • No human-authored templates needed
  • Open code from Sakana AI
  • Requires disclosure of AI use in resulting papers

Boltz

Science & Research AI
free
  • First fully open-source model to approach AlphaFold3-level structure prediction, MIT-licensed
  • Boltz-2 adds binding-affinity prediction, not just structure
  • Hostable free via community web apps (e.g. Tamarind Bio) or run locally

Evo 2

Science & Research AI
freeNew
  • DNA language model at single-nucleotide resolution with 1M base-pair context
  • Variant effect prediction, sequence completion and genome design
  • Free hosted 40B access via NVIDIA build.nvidia.com
  • Apache 2.0 code, weights and training data open; published in Nature

Chai-1 (Chai Discovery)

Science & Research AI
freemium
  • Chai-1 is free, Apache-2.0-licensed for academic and commercial use — a genuinely open structure-prediction model
  • Chai-2 (paid, enterprise) generates de novo antibodies directly from target epitopes, used by Lilly, Novartis, Pfizer
  • Autonomous AI agent that runs literature review + data analysis cycles, condensing ~6 months of research into a day per vendor
  • Publicly available via web interface and API, not an internal-only research demo
  • Kosmos itself requires a paid subscription; the free plan covers only standard agents.

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